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No.23 (1977/03) >

 
Title :Reduction of Dihaloketo-Steroids by Chromous Acetate
Authors :Kuniyoshi, Masayuki
Authors alternative :国吉, 正之
Issue Date :Mar-1977
Abstract :The reaction of chromous acetate with many kinds of 5α- and 5β-dihaloketo-steroids, which possess an oxo group on each position in ring A and B, was investigated. gem-Dihaloketones were reduced rapidly with chromous acetate in acetic acid-chlorofrm solution to give corresponding monohaloketones, accompanyed further reduced products, parent ketones. a, a' -Dihaloketones were also dehalogenated reductively to monohaloketones and small amount of parent ketones. The relative yields of reduced products varyed with the structure of dihaloketones and slightly on the mode of reaction. Several new products were also obtained. The reactivity of dihaloketones toward chromous acetate decreased in the following order: gem-dihaloketones > a, a' -dihaloketones, axial-halogen > equatorial-halogen, and bromides > chlorides.
Type Local :紀要論文
Publisher :琉球大学理工学部
URI :http://hdl.handle.net/20.500.12000/24474
Citation :琉球大学理工学部紀要. 理学編 = Bulletin of Science & Engineering Division, University of Ryukyus. Mathematics & natural sciences no.23 p.43 -49
Appears in Collections:No.23 (1977/03)

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