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No.49 (2002/12) >

 
Title :制癌剤投与マウスにおける液性免疫応答の基礎的検討
Title alternative :Basal study on humoral immune responses in mice administrated with antitumor agents
Authors :上地, 俊徳
Authors alternative :Uechi, Shuntoku
Issue Date :1-Dec-2002
Abstract :In the present study the effect on the anti-SRBC antibody response in normal mice or mice that administrated with antitumor agents, mitomycin C (MMC) or cyclophosphamide (CY), has been investigated. CY was given intraperitoneally for 4 days at a does of 50 mg./kg b. w. and MMC was given intravenously for 4 days at a does 4 mg/b. w. After the administrations, spleen weight, anti-SRBC hemagglutination titer (HA) and plaque forming cell (PFC) assay were studied in these mice. Both CY and MMC, as expected, showed suppressive effects on spleen weight, HA titer in serum and PFC response in spleen.
Type Local :紀要論文
ISSN :0370-4246
Publisher :琉球大学農学部
URI :http://hdl.handle.net/20.500.12000/3632
Citation :琉球大学農学部学術報告 = The Science Bulletin of the Faculty of Agriculture. University of the Ryukyus no.49 p.199 -203
Appears in Collections:No.49 (2002/12)

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