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Title :Triple primary malignancies of surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer as a second primary cancer detected by PET2‑[18F]‑fluoro‑2‑deoxy‑D‑glucose positron emission tomography : A case report
Authors :Maruyama, Nobuyuki
Nishihara, Kazuhide
Nakasone, Toshiyuki
Saio, Masanao
Maruyama, Tessho
Tedokon, Iori
Ohira, Tetsuya
Nimura, Fumikazu
Matayoshi, Akira
Karube, Ken-Nosuke
Yoshimi, Naoki
Arasaki, Akira
Issue Date :Jun-2018
Abstract :Second primary malignancy (SPM) is a severe issue for cancer survivors, particularly for osteosarcoma (OS) survivors. To date, the associations between subsequent SPM and OS have been well reported. Hematogenic and solid malignancies tend to occur following OS treatment. Reportedly, 2‑[18F]‑fluoro‑2‑deoxy‑D‑glucose positron emission tomography (FDG‑PET) is mainly used in OS patients for initial cancer staging, to evaluate the response of neoadjuvant chemotherapy, and when recurrence or metastasis is clinically suspected. The present case report describes a 70‑year‑old man diagnosed with three primary malignancies: jaw OS, myelodysplastic syndrome and colorectal adenocarcinoma. To the best of our knowledge, this combination of malignancies has not been reported previously. Until now, there is no specific protocol of postoperative FDG‑PET for OS patients. Few studies have described OS follow‑up methods; therefore, there is no consensus on proper follow‑up methods. In the present case report, the colorectal early‑stage SPM was observed, without any symptoms, by FDG‑PET/computed tomography. To avoid overlooking solid SPMs, it is suggested that FDG‑PET should be performed in the long‑term follow‑up of OS patients.
URL :https://doi.org/10.3892/ol.2018.8594
Type Local :雑誌掲載論文
ISSN :1792-1074
Publisher :Spandidos Publications
URI :http://hdl.handle.net/20.500.12000/45977
Citation :Oncology Letters Vol.15 no.6 p.9901 -9907
Appears in Collections:Peer-reviewed Journal Articles (Faculty of Medicine)

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