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Title :Triple primary cancer of the head and neck, skin and prostate : A case report and literature review
Authors :Maruyama, Nobuyuki
Nakasone, Toshiyuki
Arakaki, Osao
Matsumoto, Hirofumi
Maruyama, Tessho
Matayoshi, Akira
Goto, Takahiro
Saito, Seiichi
Yoshimi, Naoki
Arasaki, Akira
Nishihara, Kazuhide
Issue Date :Oct-2018
Abstract :Second primary cancer (SPC) is an important prognostic factor for patients with head and neck cancer (HNC); therefore, the association between the prognosis and development of SPC has been well‑reported. The use of 2‑[18F]‑fluoro‑2‑deoxy‑D‑glucose‑positron emission tomography (FDG‑PET) is valuable to examine cancer stage, evaluate treatment responses and investigate suspected relapses or metastases. In the present study, the case of a male patient who was diagnosed with three primary cancer types, including well to moderately differentiated squamous cell carcinoma (SCC) of the mandible, axillary cutaneous poorly differentiated SCC and prostate adenocarcinoma, was described. Among these, mandible cancer was the first diagnosed when the patient was 70 years of age. Synchronous skin and prostate cancer (PRC) types then developed 3 years later. To the best of our knowledge, this is the first report of the aforementioned combination of cancer types. Postoperative FDG‑PET was not performed as no lesions of recurrence or metastases of mandible cancer were found. Three years later, the PRC was asymptomatic and was incidentally detected by FDG‑PET performed for a preoperative evaluation of skin cancer. It was indicated that FDG‑PET could be utilized in patients with HNC due to there being no accurate FDG‑PET protocol to detect SPC over a long‑term follow‑up.
URL :https://doi.org/10.3892/ol.2018.9294
Type Local :雑誌掲載論文
ISSN :1792-1074
Publisher :Spandidos Publications
URI :http://hdl.handle.net/20.500.12000/45978
Citation :Oncology Letters Vol.16 no.4 p.5249 -5256
Appears in Collections:Peer-reviewed Journal Articles (Faculty of Medicine)

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