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Title :The 12-Item Self-Rating Questionnaire for Depressive Mixed State (DMX-12) for Screening of Mixed Depression and Mixed Features
Authors :Sinzato, Hotaka
Zamami, Yu
Kondo, Tsuyoshi
Issue Date :27-Sep-2020
Abstract :For simultaneous screening of mixed features (MF) by DSM-5 and mixed depression (MD) by Benazzi, useful symptoms were extracted from our 12-item dimensional scale for depressive mixed state (DMX-12). Subjects were 190 consecutive cases with major depressive episode (MDE) who visited our clinic. Associations between symptomatological combinations of the DMX-12 and MF or MD were analyzed using receiver operating characteristic (ROC). The rate of MF was 4.2% while that of MD was 22.6%. Eight symptoms (overreactivity, inner tension, racing/crowded thought, impulsivity, irritability, aggression, risk-taking behavior, and dysphoria) with their AUC > 0.6 for ROC curves were specially focused on distinguishing patients with MF or MD from non-mixed patients. By using these 8 symptoms, 40.5% of the overall patients were screened as positive at the same cut-off value (≥13) for both MD and MF. The AUC of ROC curve and sensitivity/specificity were well balanced together with sufficient negative predictive values. The abovementioned 8 symptoms seem to be helpful for primary screening and negative check of DMX with considerable severity during MDE.
URL :https://doi.org/10.3390/brainsci10100678
Type Local :雑誌掲載論文
ISSN :2076-3425
Publisher :MDPI
URI :http://hdl.handle.net/20.500.12000/47028
Citation :Brain Sciences Vol.10 no.10
Appears in Collections:Peer-reviewed Journal Articles (Faculty of Medicine)

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