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Title :Effects of p-Hydroxybenzaldehyde and p-Hydroxyacetophenone from Non-centrifuged Cane Sugar, Kokuto, on Serum Corticosterone, and Liver Conditions in Chronically Stressed Mice Fed with a High-fat Diet
Authors :Kinjo, Yukiko
Wada, Koji
Oe, Moena
Hou, De-Xing
Takahashi, Makoto
Issue Date :2020
Abstract :In previous studies, the non-sugar component (NSC) fraction, analyzed as 50 % methanol extract from Kokuto, showed a high in vitro antioxidant activity and strong anti-stress effect in acutely stressed mice. In addition, p-hydroxybenzaldehyde (HBA) and p-hydroxyacetophenone (HAP) were determined to be some of the antioxidative compounds in the NSC fraction. Therefore, the aim of the present study was to investigate whether NSC fraction, HBA and HAP could suppress stress response and the changes of hepatic lipids in chronically stressed mice fed a high fat diet. The results of the present study show that the NSC fraction has a high antioxidant activity in vitro, and oral administration of the fraction and HAP suppressed the secretion of stress hormone in the chronically stressed mice. We also found that the two phenolic compounds prevented hepatic lipid accumulation and peroxidation in the stressed mice.
URL :https://doi.org/10.3136/fstr.26.501
Type Local :雑誌掲載論文
ISSN :1881-3984
Publisher :Japanese Society for Food Science and Technology
URI :http://hdl.handle.net/20.500.12000/48705
Citation :Food Science and Technology Research Vol.26 no.4 p.501 -507
Appears in Collections:Peer-reviewed Journal Articles (Faculty of Agriculture)

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